Disclaimer – this post does not address all the safety issues for crystallization of CBD, Pentane and other volatiles can be very dangerous due to their low flash points. Don’t try this without consulting your safety officer and evaluating all of the possible safety concerns. As always, wear safety glasses and other personal protective gear when working in a lab.
Quality CBD crystals begin with Quality CBD distillate
The starting material should be extracted CBD oil that has been winterized and distilled. CBD distillate should be clear. Cloudiness means there are contaminants like water, waxes and fats. If the oil is cloudy try winterizing again until the oil becomes clear.
Crystallizing oil with contamination will lead to poor yields.
CBD Crystalization Equipment
A glass jacketed vessel with stirring will be used to dissolve and crystallize the CBD. A heating/cooling bath is connected to the vessel jacket and will be used to control the temperature of the vessel.
ACS grade pentane will be the solvent. This can be dangerous stuff. Consult your safety officer!
Dissolving CBD Oil
Dissolve the clear CBD oil in pentane. Make sure the jacketed vessel’s vent/condenser is connected to an appropriate blower motor or fume hood for pentane vapors. The boiling point of pentane is 36 °C. Even at lower temperatures, pentane will release many vapors. BE CAREFUL AND TAKE ALL PROPER PRECAUTIONS! Make sure the vessel condenser is cooled to -20 °C. Add 1 part pentane to 3 parts CBD oil (some oils require slightly more or less pentane) in the jacketed vessel. Turn on stirring and turn on the heating bath and set to 45 °C. Wait until the solution reaches 45 °C and all the oil has dissolved.
Precipitation
Set the bath to 5 °C. Slow the stirring. As the solution cools it will become more viscous. Adjust the stirrer to keep the RPM above 120. CBD crystals will spontaneously form or “crash out” of the pentane solution.
Collect CBD Crystals
Once precipitation stops, flush or physically remove The CBD crystals from the reactor. Vacuum filter the crystal/liquid slurry to remove the mother liquor from the CBD crystals. Rinse the crystals with ice-cold pentane to rinse impurities from the crystal surfaces. More rinses with pentane can improve poor color, but losses in total yield will occur.
Reprocess Mother Liquor
The mother liquor still contains dissolved CBD. This solution can be reprocessed! One caveat is that the mother liquor will accumulate THC over time. This sets a practical limitation to the number of crystallization.
CBD Purity
CBD distillate with 70 – 75% CBD content can be crystallized to produce CBD isolate (crystals) with a 90+% purity or higher.
CBD distillate with less than 70% CBD can be crystallized to produce CBD isolate with 85+% purity or higher.
CDB crystals can be redissolved and then recrystallized to improve the potency even further.
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I have been making my isolate with 70 + percent distillate. Could you make isolate with a lower percentage? Say like 50%?
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Hi,
Yes it is possible to crystallize CBD from low purity crude or poorly refined oil. However, low starting purity will reduce both yield and purity of the crystallized CBD. The lower purity CBD “isolate” will have more color, smell, and THC content than if you used distillate. This will cause you to need a recrystallization step which is not the end of the world but has a real cost.
Luke
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European countries have long been famous for their industrial development and scientific and technical innovation. In final decades, it and components from Europe have become famous throughout the world thanks to own reliability, advanced technologies and strict standards properties.
1. Innovation in Design and Technology
European companies that specialize in the production of industrial equipment, constantly introduce innovations in design and technological processes. Modern automation systems, smart ruling solutions and effective production processes make equipment from Europe necessary in the world market.
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European countries demanding monitor standards quality, which guarantees highest level of production and long service life of industrial equipment. Certification and conformity testing ensure that each product meets high safety and performance requirements.
3. Environmental Compatibility and Energy Efficiency
Modern industrial equipment from Europe is also renowned for its environmental compatibility and energy efficiency. Companies are actively developing and implement solutions aimed at reducing the negative impact on the environmental environment and optimizing energy consumption.
4. Flexibility and Custom Adaptation
This from Europe is flexible and adaptable to different production requirements. This enables companies to effectively implement new technologies, optimize processes and satisfy specific customer needs.
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The products of European industrial equipment manufacturers have gained worldwide recognition and trust. It is connected not only with the quality of products, and also with the high level of service provided by companies and customer support at all stages of cooperation.
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European industrial equipment and components continue to be at the forefront of global production. Innovation, quality and reliability make them a desired choice for businesses across the world seeking optimizing their production processes and improving the efficiency of their operations.
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European countries have long been famous for their factory development and scientific and technical innovation. In recent decades, it and components from Europe have become popular throughout the world because of their reliability, advanced technologies and strict standards quality.
1. Innovation in Design and Technology
European companies specializing in the production of industrial equipment, continuously introduce innovations in design and technological processes. Modern automation systems, smart ruling solutions and effective production processes make equipment from Europe in demand in the world market.
2. High Standards Qualities
European countries strictly monitor standards properties, which guarantees highest level of production and long service life of industrial equipment. Certification and conformity testing ensure that each product meets high safety and performance requirements.
3. Environmental Compatibility and Energy Efficiency
Modern industrial equipment from Europe is also renowned for its environmental compatibility and energy efficiency. Companies are intensively developing and implement solutions aimed at reducing the negative impact on the environmental environment and optimizing energy consumption.
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Industrial Equipment from Europe is flexible and adaptable to different production requirements. This enables enterprises to effectively implement new technological processes, improve processes and satisfy specific customer needs.
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The products of European industrial equipment manufacturers have gained worldwide recognition and trust. It is connected including with the quality of products, but also with the high level of service provided by companies and customer support at absolutely all stages of cooperation.
Conclusion https://www.storeboard.com/blogs/technology/bei-sensors-innovative-sensor-solutions-by-sensata-technologies/5655643
European industrial equipment and components continue to be at the forefront of global production. Innovation, quality and reliability make them a desired choice for businesses around the world committed to optimizing their production processes and improving the efficiency of own operations.
Permalink
European countries have long been famous for their industrial development and scientific and technical innovation. In recent decades, it and components from Europe have become popular throughout all over the world because of their reliability, advanced technologies and serious standards quality.
1. Innovation in Design and Development
European companies that specialize in the production of industrial equipment, continuously introduce innovations in design and technology. Modern automation systems, smart ruling solutions and effective production processes make equipment from Europe in demand in the world bazaar.
2. Highest Standards Qualities
European countries demanding monitor standards quality, which guarantees highest level of production and long lifetime of industrial equipment. Certification and conformity testing provide assurance that each product meets high safety and performance requirements.
3. Environmental Comparability and Energy Efficiency
Modern industrial equipment from Europe is also renowned for its environmental compatibility and energy efficiency. Companies are actively wanting to do and implement solutions aimed at reducing the negative impact on the surrounding environment and optimizing energy consumption.
4. Elasticity and Custom Adaptation
This from Europe is flexible and adaptable to different production requirements. This enables companies to effectively implement new technologies, optimize processes and satisfy specialized customer needs.
5. Worldwide Recognition and Trust
The products of European industrial equipment manufacturers have gained worldwide recognition and trust. It is strongly connected not only with the quality of products, and with the high level of service provided by companies and customer support at all stages of cooperation.
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European it and components continue to be at the forefront of global production. Innovation, quality and reliability make them a desired choice for businesses across the world committed to optimizing their production processes and increasing the efficiency of own operations.